Who wins?
The Binding of Isaac vs Spelunky
The Binding of Isaac wins 88% to 12%. 16 more put them in the same row. From Roguelike & Roguelite Games Tier List. Pick a side.
AlexIrl on The Binding of Isaac: thousands of hours in Repentance, nothing else comes close
throwaway92229 on Spelunky: the original roguelike platformer, everything since borrows from it
Roguelike & Roguelite Games Tier List: the full ranking