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Who wins?

Senna vs Pyke

Senna wins 58% to 42%. 148 more put them in the same row. From League of Legends: Supports Tier List. Pick a side.

sandwichenjoyer on Senna: senna support was S+ in season 2 at 53.3%. one patch later senna bot got huge too
throwaway33191 on Pyke: pyke was graded S from season 2 through season 3 start, then A by 26.19

League of Legends: Supports Tier List: the full ranking

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